10-04-2017, 09:15 PM
use of computers in pharmaceutical industry ppt
Abstract
Computer is mandatory in this advanced era and pharmacy and related subjects are not exception to it. This review mainly focuses on the various applications, softwares and use of computers in pharmacy. Computer science and technology is deeply utilized in pharmacy field everywhere like in pharmacy colleges, pharmaceutical industries, research centers, hospital pharmacy and many more. Computer significantly reduces the time, expenditure, and manpower required for any kind of work. Development of various softwares makes it trouble-free to handle huge data. In short, computers are playing critical role in pharmacy field, without computers pharmacy research will be long-lasting and expensive.
General description
While there are a number of texts dedicated to individual aspects of pharmaceutical research and development, this unique contributed work takes a holistic and integrative approach to the use of computers in all phases of drug discovery, development, and marketing. It explains how applications are used at various stages, including bioinformatics, data mining, predicting human response to drugs, and high-throughput screening. By providing a comprehensive view, the book offers readers a unique framework and systems perspective from which they can devise strategies to thoroughly exploit the use of computers in their organizations during all phases of the discovery and development process. Figures are used extensively to illustrate complex concepts and multifaceted processes. References are provided in each chapter to enable readers to continue investigating a particular topic in depth.
Table of Contents
PART I: COMPUTERS IN PHARMACEUTICAL RESEARCH AND DEVELOPMENT: A GENERAL OVERVIEW.
1. The history of computers in pharmaceutical research and development: A narrative 2. Computers as data analysis and data management tools in preclinical development 3. Statistical modeling in pharmaceutical research and development
PART II: UNDERSTANDING DISEASES: MINING COMPLEX SYSTEMS FOR KNOWLEDGE.
4. Drug discovery from historic herbal texts 5. Contextualizing the impact of bioinformatics on preclinical drug and vaccine discovery 6. Computers and systems biology for pharmaceutical research and development .
PART II: SCIENTIFIC INFORMATION HANDLING AND ENHANCING PRODUCTIVITY.
7. Information management -biodata in life sciences 8. Chemoinformatics techniques for processing chemical structure databases 9. Electronic Laboratory Notebooks 10. Strategies for using information effectively in early stage drug discovery. 11. Improving the pharmaceutical research and development process: how simulation can support management decision-making .
PART IV: COMPUTERS IN DRUG DISCOVERY.
12. Computers and protein crystallography 13. Computers, cheminformatics and the medicinal chemist 14. The challenges of making useful protein-ligand free energy predictions for drug discovery 15. Computer algorithms for selecting molecule libraries for synthesis 16. Success stories of computer-aided design 17. Pharmaceutical research and development productivity: can software help ?
PART V: COMPUTERS IN PRE-CLINICAL DEVELOPMENT.
18. Computer methods for predicting drug metabolism 19. Computers in toxicology and risk assessment 20. Computer optimization of biopharmaceutical properties 21. Computer simulations in pharmacokinetics and pharmacodynamics. rediscovering systems physiology in the 21st Century 22. Predictive models for better decisions from understanding physiology to optimizing trial design
PART VI: COMPUTERS IN DEVELOPMENT DECISION MAKING, ECONOMICS AND MARKET ANALYSIS.
23. Making pharmaceutical development more efficient . 24. Use of interactive software in medical decision making .
PART VII: COMPUTERS IN CLINICAL DEVELOPMENT.
25. Clinical data collection and management 26. Regulation of computer systems 27. A new paradigm for analyzing adverse drug events .
PART VII: FURTHER APPLICATIONS AND FUTURE DEVELOPMENT.
28. Computers in pharmaceutical formulation 29. Legal protection of innovative uses of computers in research and development 30. The ethics of computing in pharmaceutical research 31. The UltraLink: An expert system for contextual hyperlinking in knowledgemanagement 32. Powerful, predictive and pervasive: The future of computers in the pharmaceutical industry
Index.
Description
A unique, holistic approach covering all functions and phases of pharmaceutical research and development
While there are a number of texts dedicated to individual aspects of pharmaceutical research and development, this unique contributed work takes a holistic and integrative approach to the use of computers in all phases of drug discovery, development, and marketing. It explains how applications are used at various stages, including bioinformatics, data mining, predicting human response to drugs, and high-throughput screening. By providing a comprehensive view, the book offers readers a unique framework and systems perspective from which they can devise strategies to thoroughly exploit the use of computers in their organizations during all phases of the discovery and development process.
Chapters are organized into the following sections:
* Computers in pharmaceutical research and development: a general overview
* Understanding diseases: mining complex systems for knowledge
* Scientific information handling and enhancing productivity
* Computers in drug discovery
* Computers in preclinical development
* Computers in development decision making, economics, and market analysis
* Computers in clinical development
* Future applications and future development
Each chapter is written by one or more leading experts in the field and carefully edited to ensure a consistent structure and approach throughout the book. Figures are used extensively to illustrate complex concepts and multifaceted processes. References are provided in each chapter to enable readers to continue investigating a particular topic in depth. Finally, tables of software resources are provided in many of the chapters.
This is essential reading for IT professionals and scientists in the pharmaceutical industry as well as researchers involved in informatics and ADMET, drug discovery, and technology development. The book's cross-functional, all-phases approach provides a unique opportunity for a holistic analysis and assessment of computer applications in pharmaceutics.